When it comes to comfort food with a spicy Louisiana twist, Cajun Ninja Crawfish Fettuccine Recipe tops the list. This mouthwatering dish comes straight from the pages of the Cajun Ninja Cookbook, a bestselling gem on Amazon that’s become a go-to for fans of authentic Cajun cooking. The Cajun Ninja has built a reputation not only for their irresistible recipes but also for their ability to capture the heart and soul of Louisiana’s culinary traditions.
I’ll never forget the first time I tried this creamy, cheesy, and oh-so-flavorful dish—it felt like Louisiana on a plate! Crawfish, fettuccine pasta, and a sauce full of bold Cajun spices come together to create a meal that’s not only delicious but unforgettable. Leftover crawfish from a boil or a fresh pack from the store work equally well for this recipe, making it versatile and convenient.
If you love the flavors of the South and want something hearty yet easy to prepare, follow my simple steps, and you’ll have a dish that’s sure to impress your loved ones.

What Makes This Recipe Special?
This Cajun Ninja Crawfish Fettuccine recipe isn’t just another pasta dish. Here’s why:
- Authentic Louisiana Flavors: Packed with Cajun spices, seasoned crawfish, and a velvety sauce.
- Perfect Comfort Food: Creamy, cheesy, and baked to perfection, it’s satisfying and indulgent.
- Beginner-Friendly: Easy steps and common ingredients make it accessible to anyone.
- Customizable Heat: Adjust the spice level to suit your taste buds.
- Great for Leftovers: Reheats beautifully, making it perfect for meal prep.
What Is in Cajun Ninja Crawfish Fettuccine Recipe?
Here’s a detailed look at what you’ll need to make this delicious dish:
Ingredients
- Crawfish Tails (2 pounds): The heart of this dish, bringing authentic Louisiana seafood flavor.
- Butter (2 sticks): Adds richness and helps sauté the vegetables.
- Vegetables: A mix of onions (1 large, diced), bell peppers (1 large, diced), and celery (2 stalks, diced) for the classic “Holy Trinity” of Cajun cooking.
- Minced Garlic (2 teaspoons): Enhances the overall flavor.
- Rotel Tomatoes (1 can, mild): Adds a subtle tang and color to the dish.
- Cream of Chicken Soup (10.5 ounces): Creates a creamy, thick sauce base.
- Chicken Broth (14.5 ounces): Balances the richness and loosens the sauce.
- Half and Half (1 pint): For creaminess without being too heavy.
- Velveeta Cheese (Jalapeño Blend) (1 pound): Melts into the sauce for that signature cheesy texture.
- Fettuccine Noodles (2 pounds): The perfect pasta to soak up the rich sauce.
- Cajun Seasoning (to taste): Essential for that authentic spicy kick.
- Garlic Salt & Liquid Seafood Boil Concentrate: Used to season the crawfish if they aren’t pre-boiled.
Ingredients Notes
- Crawfish: If you can’t find crawfish tails, shrimp works as a great substitute.
- Rotel Tomatoes: Use a spicier version if you prefer more heat.
- Velveeta: Jalapeño blend adds a slight kick, but other blends work just as well.
- Half and Half: Creates a creamy texture without being as heavy as cream.
Recipe Variations and Substitute Ideas
This recipe is highly customizable! Here are some variation ideas:
- Seafood Swap: Use shrimp, crab, or a mix of seafood if crawfish isn’t available.
- Vegetarian Option: Replace crawfish with mushrooms and add more veggies.
- Cheese Options: Substitute Velveeta with cheddar or a mix of your favorite cheeses.
- Spice Level: Adjust Cajun seasoning or add crushed red pepper for extra heat.
Kitchen Appliances You’ll Need
- Large Stockpot (for boiling pasta)
- Medium Pot (for making the sauce)
- Large Skillet (for sautéing vegetables)
- Baking Dish (10×13 or equivalent)
- Mixing Bowls
- Spatula and Stirring Spoon
How to Make Cajun Ninja Crawfish Fettuccine
Step 1 | Prepare Crawfish
Combine crawfish tails with liquid seafood boil concentrate, Cajun seasoning, and garlic salt. Mix well and set aside.

Step 2 | Cook Fettuccine
Boil pasta in salted water, but cook it 1-2 minutes less than the package instructions to avoid overcooking during baking. Drain and set aside.

Step 3 | Sauté Vegetables
Melt butter in a large skillet. Add onions, bell peppers, and celery, and sauté on medium heat for 20-25 minutes until soft. Add garlic and cook for another 2-3 minutes.

Step 4 | Make the Sauce
Stir in Rotel tomatoes, then cook them 5 minutes, then add cream of chicken soup, and chicken broth. Slowly add the half and half, stirring continuously.

Step 5 | Melt Cheese
Add cubed Velveeta cheese in batches, stirring until melted and smooth.

Step 6 | Combine Crawfish and Pasta
Add seasoned crawfish to the sauce, followed by the cooked fettuccine. Gently toss to combine.

Step 7 | Bake
Transfer the mixture to a greased 10×13 baking dish. Cover with foil and bake at 350°F for 25 minutes.

Step 8 | Serve
Let the dish cool for 5 minutes before serving. Enjoy the creamy, flavorful masterpiece!

Tips for a Perfect Crawfish Fettuccini Alfredo
- Don’t Overcook Pasta: Slightly undercook to avoid mushy noodles after baking.
- Season Crawfish Well: Proper seasoning elevates the dish’s flavor.
- Cheese Choices: Mix Velveeta with a sharp cheese for added depth.
- Baking Dish Size: Use two smaller dishes if the portion is too large.
What to Serve With Cajun Ninja Crawfish Fettuccine
This incredible dish is a meal on its own, but here are some awesome side options that perfectly complement its rich, creamy flavors:
- Garlic Bread: Practically mandatory! It’s perfect for soaking up that incredible, cheesy sauce.
- Light, Crisp Green Salad: Tossed with a tangy vinaigrette, it helps balance out the richness of the pasta.
- Roasted Vegetables: Try asparagus or green beans for a flavorful and nutritious boost.
- Homemade Coleslaw or Cucumber Salad: For a true Louisiana experience, these cool, refreshing sides are ideal.
Storage Tips
Leftovers? Lucky you! This Cajun Ninja Crawfish Fettuccine stores beautifully. Cool the dish completely before storing in an airtight container. It’ll keep in the refrigerator for 3-4 days. When reheating, add a splash of milk to restore the creamy texture.
Pro tip: You can also freeze portions! Wrap tightly in foil and freeze for up to 2 months. Thaw in the refrigerator overnight and reheat in the oven at 325°F for about 40 minutes.
Cajun Ninja Crawfish Fettuccine Recipe FAQs
1. How spicy is this dish?
It has a mild to moderate kick. The mild Rotel and balanced seasonings create a pleasant warmth without overwhelming heat.
2. Can I make this recipe ahead of time?
Yes! You can prepare the entire dish and refrigerate before baking. Just add 10-15 minutes to the baking time.
3. How do I know when the dish is done?
The top should be golden, sauce bubbling, and pasta tender when pierced with a fork.
4. Can I make this in a slow cooker?
While possible, the baking method is recommended for the best texture and flavor development.
5. Is this an authentic Cajun recipe?
It’s a modern take on traditional Cajun cooking, inspired by classic Louisiana flavors.

Cajun Ninja Crawfish Fettuccine Recipe
Creamy, cheesy, and loaded with bold Louisiana flavors, Cajun Ninja Crawfish Fettuccine Recipe is the ultimate comfort food. Easy to make and perfect for sharing!
Ingredients
- Crawfish tails (2 lbs, frozen or fresh)
- Butter (2 sticks, unsalted)
- Cajun seasoning (1 tbsp)
- Liquid seafood boil concentrate (1 tsp)
- Garlic salt (1 tsp)
- Fettuccine pasta (2 x 16 oz packages)
- Minced garlic (2 tsp)
- Yellow onion (1 large, diced)
- Bell peppers (1 large, diced, any color)
- Celery stalk (2, diced)
- Rotel tomatoes (1 can, mild or original)
- Cream of chicken soup (1 x 10.5 oz can)
- Chicken broth (1 x 14.5 oz can)
- Half and half (1 pint)
- Velveeta cheese (1 lb, jalapeño or regular, cubed)
- Salt and pepper to taste
Instructions
- Prepare Crawfish: Combine crawfish tails with liquid seafood boil concentrate, Cajun seasoning, and garlic salt. Mix well and set aside.
- Cook Fettuccine: Boil pasta in salted water, but cook it 1-2 minutes less than the package instructions to avoid overcooking during baking. Drain and set aside.
- Sauté Vegetables: Melt butter in a large skillet. Add onions, bell peppers, and celery, and sauté on medium heat for 20-25 minutes until soft. Add garlic and cook for another 2-3 minutes.
- Make the Sauce: Stir in Rotel tomatoes, then cook them 5 minutes, then add cream of chicken soup, and chicken broth. Slowly add the half and half, stirring continuously.
- Melt Cheese: Add cubed Velveeta cheese in batches, stirring until melted and smooth.
- Combine Crawfish and Pasta: Add seasoned crawfish to the sauce, followed by the cooked fettuccine. Gently toss to combine.
- Bake: Transfer the mixture to a greased 10x13 baking dish. Cover with foil and bake at 350°F for 25 minutes.
- Serve: Let the dish cool for 5 minutes before serving. Enjoy the creamy, flavorful masterpiece!
Nutrition Information:
Serving Size: 1Amount Per Serving: Calories: 460Total Fat: 20gCholesterol: 110mgSodium: 980mgCarbohydrates: 42gProtein: 25g
Conclusion
This Cajun Ninja Crawfish Fettuccine Recipe is a Louisiana favorite that combines rich, creamy sauce with bold spices and tender crawfish. It’s a comforting dish that’s easy to make and perfect for sharing with loved ones. I hope you try this recipe and enjoy the flavors as much as I do.
Don’t forget to share your cooking experience in the comments below and follow us on Pinterest for more mouthwatering recipes.